何燕飞简介
发布时间:2021-11-07
浏览次数:2911

 

一、个人简历

何燕飞,安徽亳州人,博士,副教授;华东区中兽医研究会理事,International Journal of Biological MacromoleculesPhytomedicineCurrent Molecular Pharmacology等多个SCI期刊审稿人。主要从事中药与动物疫病防治相关方向的研究。研究内容包括:基于LC-MS/MS和化学生物信息学的中药药效物质基础及作用机制研究;中药和天然药物新兽药的开发;中兽药饲料添加剂的开发及无抗养殖。

先后主持国家自然科学基金,安徽省自然科学基金,安徽省重点研发项目,安徽省高校省级自然科学研究重点项目,企业委托横向课题等项目10余项,参与国家自然科学基金项目1项;获中国产学研合作促进会创新成果奖1项(第2完成人),中国商业联合会科技进步奖三等奖1项(第1完成人),发表专业相关论文10余篇

 

二、教育学习

20099—20136月,四川农业大学,药学(中兽药)专业,理学学士

20139—20166月,安徽农业大学,临床兽医学,硕士;

20179—20206月,浙江大学,兽医学,博士;



三、教育科研工作经历

202010—202312月,BB贝博艾弗森官方网站,讲师;

202312至今,BB贝博艾弗森官方网站副教授。


四、讲授课程

《中兽医学》、《中兽药方剂学》


五、科研情况

科研项目

1. 马齿苋生物碱调控JAK/STAT通路介导肠道巨噬细胞M1/M2平衡抗大肠杆菌性腹泻的分子机制,安徽省自然科学基金2408085MC054),主持,8.0 万,2024.92027.9在研。

2. PCFP调控JAK-STAT通路介导巨噬细胞M1/M2极化维持肠道稳态抗细菌性腹泻的分子机制,国家自然科学基金32402937),主持30万,2025.1.12027.12.31. 在研

3. 横向课题-复合山茶油功能饮品的开发经费,主持,10万,2023-2026, 在研.

4. 益生菌发酵马齿苋靶向调控肠道菌群氨基酸代谢的抗细菌性腹泻作用机制, 安徽省高校自然科学研究重点项目2023AH052634),2023AH05263410万,在研2023.92026.9.

5. 横向课题-仔猪腹泻用微生态制剂研发,主持,2万,已结题,2021-2022.

6. 基于肿瘤微环境的石斛多糖抗肿瘤的定量构效及作用机制研究,安徽省自然科学基金项目2208085QH273),主持10,结题, 2021-2023. 

7. 中药微生态制剂无抗养猪关键技术的研发产业示范,安徽省重点研究与开发计划,主持,30, 结题, 2021-2023.

8. 基于LC-MS/MS和网络药理学的黄精免疫调节活性组分的筛选及制备,高层次人才启动经费WGKQ2021023, 主持, 10 , 结题, 2020-2023.

代表性论文

1. Sun Chuanbo, Xu Guangpei, Jiang Ping, Huang Shipping, Chen Cunwu, He Yanfei*. Protective effect of ZhiziHuangqiShanzha Formula(栀子黄芪山楂方) on Aflatoxin poisoning in mice and its effect on intestinal flora. Journal of Traditional Chinese Medicine, 2024, 44(5): 926-933.

2. He Zining, He Yanfei (共一), Meng Xiang, Ge Zhiwei, Sun Hongxiang. Structural characteristics and wound-healing effects of Bletilla striata fresh tuber polysaccharide. Int J Biol Macromol. 2024 Aug 11:134679.

3. Yanfei He, Ping Jiang, Guangpei Xu, Shiping Huang, Chuanbo Sun*. Structural characteristics and anti-tumor effect of low molecular weight Dendrobium officinale polysaccharides by reconstructing tumor microenvironment. Journal of Functional Foods, 2024, 119, 106314.

4. Sun Chuanbo, Xu Y, Xu Guangpei, Ji Xu, Jiang Ping, He Yanfei*. Active fractions from Jingfang Baidu Powder alleviate Klebsiella-induced Pneumonia by inhibiting TLR4/Myd88-ERK signaling pathway. J Ethnopharmacol. 2024, 118067.

5. Yanfei He, Shiping Huang, Guangpei Xu, Ping Jiang, Lin Huang, Chuanbo Sun, Junjie Jin*, Cunwu Chen*. Structural characteristics and immunomodulation activity of a polysaccharide from purslane (Portulaca oleracea). Journal of Funtion Foods, 2023, 109(8):105781

6. Yanfei He*, Guangpei Xu, Ping Jiang, Deyong She, Lin Huang, Cunwu Chen. Anti-bacterial diarrhea effect and action mechanism of Portulaca oleracea L. water extract based on the regulation of gut microbiota and fecal metabolism, Journal of the Science of Food and Agriculture. 2023, 12810

7. Chuanbo Sun, Nuo Zhang, Guangpei Xu, Ping Jiang, Shiping Huang, Qun Zhao, Yanfei He*, Anti-tumor and immunomodulation activity of polysaccharides from Dendrobium officinale in S180 tumor-bearing mice, Journal of Functional Foods, Volume 94, 2022, 105105, https://doi.org/10.1016/j.jff.2022.105105.

8. Yanfei He*, Lin Huang, Ping Jiang, Guangpei Xu, Taotao Sun. Immunological regulation of the active fraction from Polygonatum sibiricum F. Delaroche based on improvement of intestinal microflora and activation of RAW264.7 cells. J Ethnopharmacol. 2022, 293:115240. doi: 10.1016/j.jep.2022.115240.

9. Yanfei He, Xiaoying Hu, Huifang Zhang, Xiangfeng Chen, Hongxiang Sun. Adjuvant effect of two polysaccharides from the petals of Crocus sativus and its mechanisms. Int J Biol Macromol. 2022, 204, 50-61. doi: 10.1016/j.ijbiomac.2022.01.169.

10. He Yanfei, Peng Haoxuan, Zhang Huifang, Liu Yaqin, & Sun Hongxiang. Structural characteristics and immunopotentiation activity of two polysaccharides from the petal of Crocus sativus. International Journal of Biological Macromolecules, 2021, 180, 129142.

11. Yanfei He, Tiantian Ni, Zhaoying Liu, Yiping Ye, Hongxiang Sun. Rapid annotation and structural characterization of saponins in the active fraction of Albizia julibrissin by highperformance liquid chromatography coupled with quadrupole time of flight mass spectrometry based on accurate mass database [J]. Journal of Separation Science. 2019; 42(18): 2922-2941.

12. Yanfei He, Qiaowen Wang, Yiping Ye, Zhaoying Liu, Hongxiang Sun. The ethnopharmacology, phytochemistry, pharmacology, and toxicology of genus Albizia: A review [J]. Journal of Ethnopharmacology, 2020, 257, 112677. 


六、联系方式

341281a00ek.cdb@sina.cn